![]() Researchers have found the abnormality on chromosome 15, but they have not yet identified the genes involved.īesides those related to sex, all human genes come in pairs. Females may experience scant menstruation or none at all, and most adults with PWS may not be able to reproduce. Going forward, people with PWS undergo poor sexual development during puberty. Relentless food-seeking begins and is a key feature of this stage. ![]() Phase 3 starts around the age of 8 years and can carry on to adulthood. In Phase 2, at 18 to 36 months, body weight crosses over from being lower than average to higher without any additional interest in food or calorific intake. The Prader-Willi Syndrome Association is now increasingly seeing PWS as a syndrome of multiple stages rather than just the two used initially.
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